FasterCures has often found models of medical research innovation outside the traditional establishment, specifically at nonprofit foundations like TRAIN's participating organizations.
Click through to read the full case studies below for examples of the power of venture philanthropy.
The Cystic Fibrosis Foundation (CFF) is recognized as one of the earliest and best examples of venture philanthropy in medical research. It has provided more than $1 billion in research funding since 2005, actively supports dozens of new treatments in development, nine of them FDA-approved, and has industry partners including Vertex, Pfizer, PTC Therapeutics, and Genzyme.
The Michael J. Fox Foundation (MJFF) has become the single largest funder of Parkinson's research outside the U.S. government. It has invested more than $450 million in research to date, almost 90 percent for translational research; funded testing of more than 100 therapeutic targets for Parkinson's disease (PD); and has undertaken novel industry partnerships to support early-stage promising therapeutic approaches.
The Multiple Myeloma Research Foundation (MMRF) and its sister research organization, the 22-member Multiple Myeloma Research Consortium (MMRC), have created a remarkable engine for drug discovery and development in a very short time. MMRF has raised $250 million and funded 120 institutions worldwide, has been involved in the development of six new treatments, facilitated more than 50 clinical trials through the consortium, and has 21 MMRF-funded compounds now in clinical trials.